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Center for Scientific Computation and Mathematical Modeling

Research Activities > Programs > Modeling and Simulation of Biological Channels

Modeling and Simulation of Biological Channels

October 4 - October 8, 2004

CSIC Building (#406), Seminar Room 4122.
Directions: www.cscamm.umd.edu/directions


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Acknowledgement

 

ORGANIZING COMMITTEE

Name

Affiliation

Email

Robert Eisenberg Rush Medical Center
Carl Gardner Arizona State University
Sergei Sukharev University of Maryland
Eitan Tadmor University of Maryland


SCIENTIFIC CONTENT

Biological cells exchange chemicals and electric charge with their environments through ionic channels--protein tunnels filled with ions and water--in the cell membrane walls. Signaling in the nervous system, coordination of muscle contraction including the pumping action of the heart, and ion transport in every cell and organ are carried out through ionic channels. A substantial fraction of all drugs employed by physicians act directly or indirectly on channels.

To underline the scientific importance of biological channels, the Nobel Committee awarded the 2003 Chemistry Prize to Agre and MacKinnon "for discoveries concerning channels in cell membranes."

Ionic current pulses have been observed experimentally in a wide variety of channels in the membranes of many types of cells. These current pulses are rectangular wave in shape with constant heights and are distributed stochastically in time. The workshop will focus on the hierarchy of mathematical models (from discrete to continuum) for ion transport in the channel and surrounding baths and the gating mechanism for turning the ionic current on and off, as well as numerical simulations and mathematical analysis (asymptotics, inverse problems, etc.) of the models.


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ACKNOWLEDGEMENT


FUNDING

A limited amount of funding for participants at all levels is available, especially for researchers in the early stages of their career who want to attend the full program.


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INVITED PARTICIPANTS

Name

Affiliation

Rush Medical Center
University of Texas at Austin
Dirk GillespieRush Medical Center
University of Maryland
Joyce McLaughlinRPI
Boaz Nadler Yale University
University of Miami Medical Center
University of Illinois
Illinois Institute of Technology
Zeev SchussTel Aviv

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INFORMATION FOR PARTICIPANTS

CSCAMM Visitor Guide: www.cscamm.umd.edu/visitors


CONTACT

Center for Scientific Computation And Mathematical Modeling (CSCAMM)
Computer Science Instructional Center (Building #406)
University of Maryland, College Park
College Park, MD 20742-3289

Email:

Web: //www.cscamm.umd.edu/programs/bic04


POSTER

Coming Soon


PHOTOS

Will be posted during and after the program


SUGGESTED ACTIVITIES

Coming Soon

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